The College was established as Nagarjuna Sagar Engineering College in 1965 by the Government of Andhra Pradesh. The College was initially under the administrative control of the Department of Technical Education, and affiliated to Osmania University, Hyderabad. With the formation of Jawaharlal Nehru Technological University in 1972, it became a constituent college of the University and was renamed as JNTU College of Engineering, Hyderabad. After being located in temporary buildings, the college was shifted to a hundred acre site at Kukatpally, on the Bombay Highway in 1984 which also houses the main campus of the University. Hyderabad is the Capital of Andhra Pradesh with a population of over 1, 00, 00,000 and is well connected with Air, Train and Bus.

The city is over 400 year old with historic monuments as tourist’s attraction. The Industrial Consultancy Unit of the college is very active in offering the expertise of the staff in various fields such as Structural Engineering, Geotechnical Engineering, Survey, and Electrical Engineering. The college presently has two boys hostels and one Girls Hostel. The college provides Hostel facilities for about 400 boys and 125 girls. Because of growing demand for students hostels two more hostels are being constructed one for Boys and the other for girls which will accommodate 200 students each. These new hostels are near completion. There is a University Guest house with 30 rooms to accommodate guests and invitees. The guest house has attached dinning hall. The college, in addition to, regular departments has two research centres viz. Centre for Energy Studies and Centre for Transportation Engineering.